Abstract Library

#3074 Medullary Thyroid Carcinoma and DIPNECH: An Unexpected Association

Introduction: Medullary thyroid carcinoma (MTC) is a neuroendocrine tumour of the C-cells of thyroid gland. Diffuse idiopathic pulmonary neuroendocrine cells hyperplasia (DIPNECH) is a rare condition, thought to be primarily a neuroendocrine proliferative process which can develop into carcinoid tumours.

Conference: 17th Annual ENETSConcerence (2020)

Presenting Author:

Authors: Lima Ferreira J, Marques B, Elvas A, Simões de Carvalho F, Fonseca A,

Keywords: medullary thyroid cancer, DIPNECH, neuroendocrine tumour, carcinoid tumour, pulmonary nodules,

#3049 Organoid Models of Neuroendocrine Cell Growth and Tumorigenesis

Introduction: A paucity of in vitro and in vivo models has limited the study of Neuroendocrine neoplasms (NENs). Moreover, little is known about normal neuroendocrine (NE) cells and how they contribute to NEN formation.

Conference: 17th Annual ENETSConcerence (2020)

Presenting Author:

Authors: Dayton T, Den Hartigh L, Levy S, van den Berg J, Kok N,

Keywords: Organoids, NENs, pulmonary neuroendocrine cells,

#2754 Somatostatin Analogs (SSA) in Patients with Symptomatic Diffuse Idiopathic Pulmonary Neuroendocrine Cell Hyperplasia (DIPNECH)

Introduction: DIPNECH is characterized by a proliferation of pulmonary neuroendocrine cells and multifocal neuroendocrine tumorlets and/or tumors. Although usually indolent, DIPNECH can cause chronic cough and dyspnea. There is very limited information on treatment.

Conference: 17th Annual ENETSConcerence (2020)

Presenting Author:

Authors: Al-Toubah T, Strosberg J, Halfdanarson T, Oleinikov K, Gross D,

Keywords: DIPNECH, Somatostatin analogs, Octreotide, Lanreotide,

#2002 Pulmonary Function Test Physiology and Progression in Diffuse Idiopathic Pulmonary Neuroendocrine Cell Hyperplasia

Introduction: Diffuse idiopathic pulmonary neuroendocrine cell hyperplasia (DIPNECH) is a rare condition characterised by a generalised proliferation of pulmonary neuroendocrine cells within the respiratory epithelium. Little is known of its affects on pulmonary function both at the time of diagnosis and prospectively.

Conference: 15th Annual ENETSConcerence (2018)

Presenting Author: Barlow J

Authors: Barlow J, Ryan D, Mansoor W, Howell M, Clayton N,

Keywords: Neuroendocrine, Cell, Pulmonary, Function, Hyperplasia, Pulmonary function, Diffuse idiopathic pulmonary neuroendocrine cell hyperplasia, DIPNECH, Physiology,

#30 Diffuse Idiopathic Pulmonary Neuroendocrine Cell Hyperplasia

Introduction: Normal adult lungs contain scattered pulmonary neuroendocrine cells (PNEC). Reactive PNEC hyperplasia is commonly observed in persons who live at high altitude, in cigarette smokers, and in numerous lung diseases. Diffuse Idiopathic Pulmonary Neuroendocrine Cell Hyperplasia (DIPNECH) is a rare entity in which PNEC hyperplasia appears without predisposing conditions. According to the 1999 WHO lung tumor classification, DIPNECH is thought to be primarily a neuroendocrine proliferative process, which can be associated with carcinoid tumors and with a clinical picture of constrictive obliterative bronchiolitis. To date, available data regarding the treatment and the prognosis of this rare condition is limited.

Conference: 7th Annual ENETSConcerence (2010)

Presenting Author: Grozinsky-Glasberg S

Authors: Gorshtein A, Barak D, Shimon I, Gross D, Grozinsky-Glasberg S,

Keywords: DIPNECH, neuroendocrine, hyperplasia, somatostatin analogues,